Amilin Depressive illness

Amilin®

Active Ingredient
Amitriptyline Hydrochloride

Indication
Depressive illness, particularly with anxiety & nocturnal enuresis in children.

Dosage & Administration 
25-50 mg a day in divided dose.

Contraindication & Precaution 
Myocardial infarction; arrythmias, particularly heartblock of any degree; mania; severe liver disease. Caution in patients with a history of epilepsy, glaucoma, urinary retention, prostatic hypertrophy, constipation, cardiac disease, diabetes, pregnancy, hepatic impairment, thyroid disease, increased intraoccular pressure, psychoses (may aggravate mania).

Side Effect 
Hypotension, syncope, postural hypotension, hypertension, tachycardia, palpitations, myocardial infarction, arrythmias, & heart block stroke. Confusional states, disorientation, delusions, & hallucinations. Dry mouth, blurred vision, mydriasis, increased intraoccular pressure, hyperplasia. Skin rash, urticaria, & photosensitization. Bone-marrow depression, Gastrointestinal: Nausea, epigastric distress, vomiting anorexia, diarrhoea. Testicular swelling, gynaecomastia; breast enlargement, galactorrhoea. Dizziness, weakness, fatigue, headache, weight loss.

Drug Interaction 
Monoamine oxidase inhibitors, adrenaline, epinephrine, isoprenaline, noradrenaline, CNS depressant, Alcohol, Cemitidine.

Use in Pregnancy & Lactation 
The drug should be used during pregnancy & lactation if potential benefit justifies the potential risk to the fetus.

Preparation 
10 mg & 25 mg Tablet.