Active Ingredient
Losartan Potassium.
Indication
Hypertension: Angilock® is indicated for the treatment of hypertension. It may be used alone or in combination with other antihypertensive agents, including diuretics. Hypertensive patients with Left Ventricular Hypertrophy: Angilock® is indicated to reduce the risk of stroke in patients with hypertension & left ventricular hypertrophy. Nephropathy in Type 2 Diabetic Patients: Angilock® is indicated for the treatment of diabetic nephropathy with an elevated serum creatinine & proteinuria (urinary albumin to creatinine ratio ≥300 mg/g) in patients with type 2 diabetes & a history of hypertension.
Dosage & Administration
Adult hypertensive patients: The usual starting dose of Angilock® is 50 mg once daily. 25 mg .
Contraindication & Precaution
Losartan is contraindicated in patients who are hypersensitive to any component of this product. Do not co-administer aliskiren with Losartan in patients with diabetes. It is also contraindicated during 2nd & 3rd trimester of pregnancy & in severe hepatic impairment. In patients who are intravenously volume depleted (e.g. those treated with high-dose diuretics), symptomatic hypotension may occur. These conditions should be corrected prior to the administration of losartan or a lower starting dose should be used. A lower dose should be considered for patients with a history of hepatic impairment. Losartan should not be used with potassium-sparing diuretics.
Side Effect
Dizziness, rash, Angioedema involving swelling of the face, lips and/or tongue & serious hypotension (particularly on initiating treatment in salt-depleted patients) or renal failure (mainly in patients with renal artery stenosis) may be encountered during Losartan potassium treatment.
Use in Pregnancy & Lactation
Pregnancy Catagory D. Losartan potassium should not be used in pregnancy & if pregnancy is detected Losartan potassium should be discontinued as soon as possible. Losartan potassium should not be used in lactating mother.
Drug Interaction
No drug interaction of clinical significance has been identified.
Preparation
25 mg, 50 mg & 100 mg Tablet.
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