Cefobac
(125mg/5ml)/250/500 mg
Active Ingredient
Cefuroxime.
Indication
1. Upper respiratory tract infections, for example, ear, nose & throat infections such as otitis media, sinusitis, tonsillitis & pharyngitis. 2. Lower respiratory tract infections: for example, acute bronchitis, acute exacerbations of chronic bronchitis & pneumonia. 3. Skin & soft tissue infections: such as furunculosis, pyoderma, & impetigo. 4. Genito-urinary tract infections: such as pyelonephritis, urethritis, & cystitis. 5. Gonorrhoea: acute uncomplicated gonococcal urethritis, & cervicitis. 6. Early Lyme disease & subsequent prevention of late Lyme disease.
Dosage & Administration
Adults : 250 mg b. i.d. upto 500 mg b. i. d. should be given. For urinary tract infections a dose of 125 mg b.i.d is usually adequate. A single dose of one gram is recommended for the treatment of uncomplicated gonorrhoea. Children : The usual dose is 125 mg b. i. d., or 10 mg/kg b. i. d. to a maximum of 250 mg daily. The usual course of therapy is 7-10 days. Cefuroxime should be taken after food for optimum absorption. Parenteral Dosage : Adults : 750 mg to 1.5 g IM or IV every 8 hourly, usually 5 to 10 days. Infants & children (>3 months) : 50 to 100 mg/kg/day in equally divided doses every 6 to 8 hours.
Contraindication & Precaution
Known allergy to Cephalosporins. As with other antibiotics, prolonged use of Cefuroxime may result in the over growth of non-susceptible organisms (e.g. Candida, Enterococci, Clostridium difficile), which may require interruption of treatment. Pseudomonas colits has been reported with the use of broad-spectrum antibiotics, therefore, it is important to consider its diagnosis in patients who develop serious diarrhoea during or after antibiotic use.
Side Effect
Nausea & vomiting.
Use in Pregnancy & Lactation
While all antibiotics should be avoided in the first trimester if possible. Cefuroxime has been safely used in later pregnancy to treat urinary & other infections. Caution should be exercised when Cefuroxime is administered to a nursing mother.
Preparation
125 mg, 250 mg & 500 mg Tablet, 125 mg/5 ml Suspension, 750 mg IM/IV Injection, 1.5 gm IV injection
(125mg/5ml)/250/500 mg
Active Ingredient
Cefuroxime.
Indication
1. Upper respiratory tract infections, for example, ear, nose & throat infections such as otitis media, sinusitis, tonsillitis & pharyngitis. 2. Lower respiratory tract infections: for example, acute bronchitis, acute exacerbations of chronic bronchitis & pneumonia. 3. Skin & soft tissue infections: such as furunculosis, pyoderma, & impetigo. 4. Genito-urinary tract infections: such as pyelonephritis, urethritis, & cystitis. 5. Gonorrhoea: acute uncomplicated gonococcal urethritis, & cervicitis. 6. Early Lyme disease & subsequent prevention of late Lyme disease.
Dosage & Administration
Adults : 250 mg b. i.d. upto 500 mg b. i. d. should be given. For urinary tract infections a dose of 125 mg b.i.d is usually adequate. A single dose of one gram is recommended for the treatment of uncomplicated gonorrhoea. Children : The usual dose is 125 mg b. i. d., or 10 mg/kg b. i. d. to a maximum of 250 mg daily. The usual course of therapy is 7-10 days. Cefuroxime should be taken after food for optimum absorption. Parenteral Dosage : Adults : 750 mg to 1.5 g IM or IV every 8 hourly, usually 5 to 10 days. Infants & children (>3 months) : 50 to 100 mg/kg/day in equally divided doses every 6 to 8 hours.
Contraindication & Precaution
Known allergy to Cephalosporins. As with other antibiotics, prolonged use of Cefuroxime may result in the over growth of non-susceptible organisms (e.g. Candida, Enterococci, Clostridium difficile), which may require interruption of treatment. Pseudomonas colits has been reported with the use of broad-spectrum antibiotics, therefore, it is important to consider its diagnosis in patients who develop serious diarrhoea during or after antibiotic use.
Side Effect
Nausea & vomiting.
Use in Pregnancy & Lactation
While all antibiotics should be avoided in the first trimester if possible. Cefuroxime has been safely used in later pregnancy to treat urinary & other infections. Caution should be exercised when Cefuroxime is administered to a nursing mother.
Preparation
125 mg, 250 mg & 500 mg Tablet, 125 mg/5 ml Suspension, 750 mg IM/IV Injection, 1.5 gm IV injection
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